Oral tumors peripheral odontogenic fibromas vca animal. Cemento ossifying fibroma is a benign fibroosseous maxillary tumor belonging to the same category as fibrous dysplasia and cement ossifying dysplasia. Peripheral ossifying fibroma mohiuddin k, priya n s, ravindra s. Occasionally treated by curettage enucleation, this conservative.
Peripheral ossifying fibroma pof is a lesion of the gingival tissues representing up to 2% of all oral lesions that are biopsied. Fibrous dysplasia is first diagnosed in infancy and childhood 7, mainly in the first and second decades 8. Differential diagnosis consisted of pyogenic granuloma, peripheral giant cell granuloma pgcg, irritational fibroma or peripheral odontogenic fibroma. Peripheral ossifying fibroma is a benign swelling of the gum, most commonly seen in teenagers and young adults. Peripheral ossifying fibroma is a solitary growth on the. However, certain authors have stated that peripheral ossifying fibroma is a variant of central ossifying fibroma and, therefore, a neoplastic process. Careful clinical examination and histopathology findings should be correlated. Clinically differentiating one from the other as a specific lesion is often difficult and requires histopathology examination. Pof is an occasional growth of the anterior region of mandible and accounts for 3.
Here we present a case of 18year old female having slow growing painless swelling on left side of mandible over 2year period. The peripheral ossifying fibroma pof is a relatively uncommon reactive lesion of the gingiva, associated with mineralization and. Additionally, cemento ossifying fibroma may have areas of cementum, appearing as psammoma bodies embedded in a benign fibrous stroma. In the world health organization international classification of tumors of domestic animals, among the tumors formed in the bones of the upper alimentary system and in bones and joints, osteoma, ossifying fibroma, myxoma, and chondroma are classified as benign, while osteosarcoma, chondrosarcoma, and multilobular bone tumor are classified as malignant 3, 9. They can be further subclassified as peripheral odontogenic fibromas and acanthomatus ameloblastomas. Histopathological characteristics of an ossifying fibroma. Trabecular and psammomatoid patterns, myxomatous matrix. In the 2005 who histological classification of odontogenic tumors, this tumor is referred to as ossifying fibroma but in this article, the term cemento ossifying tumor is used to differentiate from peripherally occurring ossifying fibromas.
Due to its clinical and histopathological similarities, some pofs are believed to develop initially as a pyogenic granuloma that undergoes fibrous. The varying clinical presentations of peripheral ossifying fibroma. He also suggested that the name peripheral ossifying fibroma should be retained for this lesion. A histopathological examination revealed a covering of partially parakeratinized stratified squamous epithelium proliferating into the underlying connective tissue. Jul 14, 2016 cemento ossifying fibroma cof is a distinct form of a benign fibroosseous tumor, affecting predominantly the craniofacial region. Excision and repair of the peripheral ossifying fibroma.
Peripheral ossifying fibroma is a reactive lesion and peripheral odontogenic fibroma is an extraosseous variant of central odontogenic fibroma. Considerable confusion has prevailed in the nomenclature of peripheral ossifying fibroma with various synonyms being used, such as peripheral cementifying fibroma, ossifying fibroepithelial polyp, peripheral fibroma with osteogenesis. Extensive presentation of central ossifying fibroma treated. Peripheral ossifying fibroma pof is a gingival nodule composed of a cellular fibroblastic connective tissue stroma associated with the formation of randomly dispersed foci of a mineralized product consisting of either bone woven and lamellar, cementum like material and dystrophic calcifications. Peripheral ossifying fibroma, also known as ossifying fibrous epulis, is a gingival nodule which is composed of a cellular fibroblastic connective tissue stroma which is associated with the formation of randomly dispersed foci of mineralised products, which consists of bone, cementumlike tissue, or a dystrophic calcification. Central lesion of bone with variable fibrous proliferation of round, polyhedral or spindly cells and calcifications. It is derived from cells of the periodontal ligament and is usually classified as a reactive hyperplasia but sometimes as a benign neoplasm. Furthermore, the pof has a propensity to occur in the incisor cuspid area affecting maxilla more than the mandible. Peripheral ossifying fibroma is thought to be either reactive or neoplastic in nature 2,3. Peripheral ossifying fibroma definition of peripheral. Peripheral ossifying fibroma, some rare findings chaturvedy v. Nov 16, 2016 unusual findings in common peripheral ossifying fibromas. What is peripheral ossifying fibroma peripheral ossifying fibroma is a benign swelling of the gum, most commonly seen in teenagers and young adults.
Nov 06, 2011 peripheral ossifying fibroma pof is a nonneoplastic entity, which occurs on the gingiva in response to trauma or irritation. Careful clinical examination and histopathology findings should be correlated to conclude the final diagnosis. First description of ossifying fibroma was given by menzel in 1872 while the term was given by montgomery in 1927. Pdf here, we present a case report of peripheral ossifying fibroma pof in an. Peripheral ossifying fibroma pof is a relatively uncommon, gingival overgrowth, which comprises of fibroblastic tissue that contains one or more mineralized tissues.
Histopathologic differential diagnoses thorakkal shamim department of dentistry, government taluk head quarters hospital, nilambur, india peripheral ossifying fibroma is a benign neoplasm that usually develops from gingiva, presenting as an. Central cemento ossifying fibroma is a fibroosseous lesion causing slow expansion of the involved bone and is usually manifested after attaining significant growth. It is a reactive lesion of connective tissue and is not the softtissue counterpart of central ossifying fibroma. Many of the fibrous growths originate from underneath the periodontium, similar to peripheral ossifying fibroma pof. Peripheral odontogenic fibroma is an uncommon neoplasm that is believed to arise from odontogenic epithelial rests in periodontal ligament or attached gingiva itself. A series of 207 cases of peripheral ossifying fibroma was analyzed both clinically and histologically. Peripheral ossifying fibroma is a gingival growth, usually arising from interdental papilla and occurring frequently in the anterior maxilla. Regarding clinical aspects, peripheral ossifying fibroma is usually presented as a. Other synonyms of cemento ossifying fibroma besides ossifying fibroma include 7. It is considered to be the extraosseous counterpart of the central odontogenic fibroma. Report of two cases shipra arora, arundeep kaur lamba, farrukh faraz, shruti tandon, kirti chawla case report abstract peripheral ossifying fibroma pof is a nonneoplastic growth on the gingiva thought to arise from the periodontal ligament. Cementoossifying fibroma radiology reference article. Excisional biopsy was performed after explaining the procedure and obtaining consent from the patient. Peripheral ossifying fibroma is a relatively common gingival growth of reactive rather than neoplastic in nature.
Other terms used in reference to pof are peripheral cementifying fibroma, peripheral fibroma with cementogenesis, peripheral fibroma with osteogenesis, peripheral fibroma with calcification, calcified or ossified fibrous epulis, and calcified fibroblastic granuloma. The histomorphogenic spectrum of peripheral ossifying fibroma. Osteofibrous dysplasia is considered as a separate pathological entity in view of its different presentation and treatment, although histopathologically similar to ossifying fibroma. Discrete mass that is well delineated from surrounding bone, no encapsulation, tanwhite, rubbery cut surface, firm to gritty. Intraoral ossifying fibromas have been described in the literature since the late 1940s. Because of its overwhelming incidence on the gingiva, the. Peripheral ossifying fibroma has to be differentiated from traumatic fibroma, peripheral giant cell granuloma, pyogenic granuloma, and peripheral odontogenic fibroma. Central ossifying fibroma is a benign slowgrowing tumor of mesenchymal origin and it tends to occur in the second and third decades of life, with predilection for women and for the mandibular premolar and molar areas.
Jul 03, 2017 peripheral ossifying fibroma pof is one of the few reactive lesions of the gingiva which are clinically similar in presentation. Peripheral ossifying fibroma pof represents a rare separate entity of reactive benign lesion of connective tissue origin, not being the soft tissue counterpart of central ossifying fibroma. Gingiva, ossifying fibroma, peripheral ossifying fibroma. The present article is a case report related to peripheral ossifying fibroma in a year male who reported with a painless growth in the mandibular. The histopathological features were diagnostic of peripheral ossifying fibroma. Many names have been given to similar lesions, such as epulis, peripheral fibroma with calcification, peripheral ossifying fibroma, calcifying fibroblastic granuloma, peripheral cementifying fibroma, and peripheral fibroma with cementogenesis. Tissue was repositioned using 50 polypropylene wire and the piece was sent to histopathological examination. Peripheral cemento ossifying fibroma shows parakeratinised epithelium and well cellularised connective tissue containing mineralized components ranging from bone to cementum. Ossifying fibroma and fibrous dysplasia of the jaw are maxillofacial fibroosseous lesions that should be distinguished each other by a pathologist because they show distinct patterns of disease. Ossifying fibroma and fibrous dysplasia of the jaw are maxillofacial fibroosseous lesions that should be distinguished each other by a pathologist because they show distinct patterns of. Fibrous dysplasia and ossifying fibroma an advent in their. Shipra arora et al treatment of peripheral ossifying fibroma.
Treatment of peripheral ossifying fibroma using er,cr. Peripheral ossifying fibroma pof is a nonneoplastic entity, which occurs on the gingiva in response to trauma or irritation. Sometimes, the classic clinical, radiologic or pathologic features of fibrous dysplasia or ossifying fibroma may not be evident, but overlapping features of both may be seen. Pof has been cited in the literature under various names such as cemento ossifying fibroma, peripheral fibroma with osteogenesis, peripheral odontogenic fibroma, calcifying fibroblastic granuloma etc 6. Peripheral ossifying fibroma pof is a lesion of the gingival tissues 15 representing up to 2% of all oral lesions that are biopsied 1. The term ossifying fibroma includes lesions with similar histological compositions and different forms of clinical behavior.
Peripheral ossifying fibroma pof has been cited in the literature under various names such as cemento ossifying fibroma, peripheral fibroma with osteogenesis, peripheral odontogenic fibroma, calcifying fibroblastic. Other terms used in reference to pof are peripheral cementifying fibroma, peripheral fibroma with cementogenesis, peripheral fibroma with osteogenesis, peripheral fibroma with calcification, calcified. Almost 60% of the lesions occurred in the maxilla, and in both jaws more than 50% occurred in. Unusual findings in common peripheral ossifying fibromas. Peripheral odontogenic fibroma formerly known as fibromatous and ossifying epulis is a benign, often slowgrowing tumor that arises from periodontal structures. Mar 30, 2017 intraoral ossifying fibromas have been described in the literature since the late 1940s. Many names have been given to similar lesions, such as epulis, peripheral fibroma with calcification, pof, calcifying fibroblastic granuloma, peripheral cementifying fibroma, peripheral fibroma with cementogenesis and peripheral cemento ossifying fibroma.
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